The best Innovation ETFs
How to invest in innovative technologies using ETFs

How do I invest in innovative technologies?
Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.
In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 24 ETFs available.
iSTOXX® FactSet Breakthrough Healthcare performance
Innovation ETFs in comparison
When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.
Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart
ETF name ISIN | Fund size in m EUR | TER in % | Use of profits | Fund domicile | Replication method | |
---|---|---|---|---|---|---|
iShares Healthcare Innovation UCITS ETFIE00BYZK4776 | 788 | 0,40% p.a. | Accumulerend | Ierland | Geoptimaliseerde sampling | |
Amundi MSCI Disruptive Technology UCITS ETF AccLU2023678282 | 132 | 0,45% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
ARK Innovation UCITS ETF USD AccumulatingIE000GA3D489 | 93 | 0,75% p.a. | Accumulerend | Ierland | Volledige replicatie | |
UBS Solactive China Technology UCITS ETF USD accLU2265794276 | 91 | 0,47% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 | 88 | 0,59% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF AccIE00BM8QS095 | 86 | 0,49% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Amundi MSCI China Tech UCITS ETF EUR AccLU1681043912 | 60 | 0,55% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
L&G Healthcare Breakthrough UCITS ETF USD AccIE00BK5BC677 | 55 | 0,49% p.a. | Accumulerend | Ierland | Volledige replicatie | |
UBS MSCI USA Tech 125 Universal UCITS ETF USD accIE0003B4BV34 | 26 | 0,18% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Amundi MSCI China Tech UCITS ETF USD AccLU1681044050 | 24 | 0,55% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
UBS Solactive China Technology UCITS ETF hEUR accLU2265794946 | 19 | 0,50% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 | 19 | 0,49% p.a. | Accumulerend | Ierland | Volledige replicatie | |
WisdomTree Megatrends UCITS ETF USDIE0000902GT6 | 18 | 0,50% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 1CLU2376679564 | 15 | 0,44% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
Harbor Health Care UCITS ETF AccumulatingIE00BJQTJ848 | 15 | 0,89% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Xtrackers World Green Transition Innovators UCITS ETF 1CLU2859392081 | 11 | 0,35% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
ARK Genomic Revolution UCITS ETF USD AccumulatingIE000O5M6XO1 | 8 | 0,75% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Xtrackers MSCI Innovation UCITS ETF 1C 1CIE0006FFX5U1 | 6 | 0,30% p.a. | Accumulerend | Ierland | Volledige replicatie | |
First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 | 4 | 0,70% p.a. | Accumulerend | Ierland | Volledige replicatie | |
VanEck Genomics and Healthcare Innovators UCITS ETF AIE000B9PQW54 | 4 | 0,35% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Xtrackers World Small Cap Green Transition Innovators UCITS ETF 1CLU2859297330 | 4 | 0,45% p.a. | Accumulerend | Luxemburg | Volledige replicatie | |
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 1CIE000KD0BZ68 | 3 | 0,30% p.a. | Accumulerend | Ierland | Volledige replicatie | |
First Trust Alerian Disruptive Technology Real Estate UCITS ETF AccIE000RN036E0 | 2 | 0,60% p.a. | Accumulerend | Ierland | Volledige replicatie | |
Invesco ChiNext 50 UCITS ETF AccIE000AWRDWI7 | 2 | 0,49% p.a. | Accumulerend | Ierland | Volledige replicatie |
Source: justETF.com; As of 26-05-2025
Return comparison of all innovation ETFs
The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.
Source: justETF.com; As of 30-04-2025; Calculations in EUR including dividends